Acetophenone (CAS No. 98-86-2, EC No. 202-708-7), with chemical name ‘1-
phenylethanone’, is an aromatic compound commonly used in cosmetics primarily as perfuming agent, valued for its sweet and floral scent.
In light of the data provided and taking into consideration the possible classification as ‘Repr.1B’ under Regulation (EC) No 1272/2008 (CLP Regulation), the SCCS
considers Acetophenone safe when present up to a maximum concentration of 100 ppm (0.01%) in cosmetic products, taking also into account sources of exposure other than cosmetics (food, tobacco smoking).
The SCCS concludes that, under the evaluated conditions of use, acetophenone is unlikely to pose a risk to human health. However, the opinion remains preliminary, and stakeholders are invited to provide additional scientific data or comments before the final conclusion is adopted. This includes any new toxicological studies or refined exposure assessments that could influence the risk characterization.
Ref: https://health.ec.europa.eu/document/download/bef7f14c-5d4d-46e8-92da-026d88fd92bc_en?filename=sccs_o_311.pdf
